This question has been answered by tm2000. See the first response.
Have you looked at your dev tools panel to look at possible error before or after clicking the save button?I haven't. I'm not sure how to interpret the data that would appear there though.
Hm. That would be the only angle I can think of right now to start debugging. Could also be there is no response at all or maybe a 500 error. Then you could compare if Safari and Firefox are sending the same sets of data.
If you get a response, the value returned could give you some clue.
Other than that I have no experiences with an error like that that could help, sorry.
Any Firefox plugins that might be interfering?
Try repairing the table in the DB with PhpMyAdmin.
One final potential culprit, as always, is mod_security. In my experience, mod_security is responsible for the majority of cases where resources fail to save.
Tables: Repair all of them. Select all and use the "With Selected" drop-down at the bottom of the grid.
mod_security: The only solution is to file a ticket with your host. They should be able to tell from their logs if mod_security is being triggered. As a diagnostic, you could try saving an empty resource repeatedly. If that hangs, it's not mod_security. Also, if the same resource that didn't save will save on subsequent tries without changing the content or TVs, it's not mod_security.
You can try watching the Network tab in Chrome Dev. tools when saving resources. When it hangs, you can select requests and look at the Response tab. You might see a PHP error there or some other indication of the problem.
Tables: Repair all of them. Select all and use the "With Selected" drop-down at the bottom of the grid.
mod_security: The only solution is to file a ticket with your host. They should be able to tell from their logs if mod_security is being triggered. As a diagnostic, you could try saving an empty resource repeatedly. If that hangs, it's not mod_security. Also, if the same resource that didn't save will save on subsequent tries without changing the content or TVs, it's not mod_security.
You can try watching the Network tab in Chrome Dev. tools when saving resources. When it hangs, you can select requests and look at the Response tab. You might see a PHP error there or some other indication of the problem.