I guess the question we should be asking is how much HTML do you know?
Can you slice a template to html? That is all you need to know in order to get a site working in MODx the rest can all be done by reading the documentation really it’s that simple.
As for wayfinder and creating navigations can be a bit confusing at first but if you know how to create menus from unordered lists you will better understand how wayfinder works if you read the
wayfinder ebook
If you need help you can always post here in the forums we are all willing to help, it’s the only way the community will grow.
You need to be able to visualize a website in pieces thats pretty much how MODx treats it’s sites as pieces that are all merged to create an awesome site.
Check marys tutorials they are very easy to follow:
http://codingpad.maryspad.com/
Have fun, never stay in doubt, always ask if you are stuck but also do some research before you post, we are MODx and we are here to help