I am currently using BlueHost for all my hosting for my sites. They implement SimpleScripts for one click installs...
I installed one site running 2.2.0-pl2 no problem
installed another instance for another site - 2.2.1-pl - and i got something similar to the OP. manager page wasnt properly themed and if i got logged in there was no styling at all.
tracked it down to a bad config in the install.
core/config/config.inc.php
$modx_connectors_url= '//connectors/';
$modx_manager_url= '//manager/';
$modx_base_url= '//';
$modx_assets_url= '//assets/';
if you notice it has an extra / in the url entries
this is what it should look like:
$modx_connectors_url= '/connectors/';
$modx_manager_url= '/manager/';
$modx_base_url= '/';
$modx_assets_url= '/assets/';
you might check your config file to verify as well. just a suggestion if it happens to be a similar issue.