It certainly is possible.
Here are some rules I’m using :
// Role Control
// Role 2 = Editor
mm_hideTabs('settings,meta,preview', '2', '');
mm_hideFields('alias,menutitle,longtitle,link_attributes,introtext,parent', '2');
mm_hideSections('access', '2', '');
// General Template Control
// tpl 5 = Sitemap
// tpl 4 = Generic
// tpl 3 = Main
// tpl 1 = Default
// tpl 0 = Blank
mm_hideSections('tvs', '2', '5,4,1');
mm_hideTemplates('5,4,1', '2');
mm_hideFields('content', '2', '0');
mm_moveFieldsToTab('pub_date,unpub_date', 'general', '2', '0'); // Move the publication date field to the general tab for users with role "2"
mm_renameSection('content', 'Specification details', '2', '3');
There are quite extensive docs in the ManagerManager folder to give you more ideas.