If Romain’s suggestions don’t work, take another look at the config.core.php files in these locations:
§ MODX root directory
§ /manager/
§ /connectors/
§ /setup/includes/
Then double-check both the paths and the URLs in the core/config/config.inc.php file -- especially the URLs. It’s possible that the URLs have an unnecessary prefix:
$modx_connectors_url= '/yoursite/connectors/';
$modx_base_url= '/yoursite/';
instead of
$modx_connectors_url= '/connectors/';
$modx_base_url= '/';
This happened to me when moving a site from a localhost install to a remove server. Even though both sites were in subdirectories, the domain name was unnecessary on the remote. Look at the URL shown when you try to access the manager, that will be an important clue.