This is interesting to me as I work mainly with NPOs. From what I understand CiviCRM is a module for Drupal and/or Joomla. Does the adaptation of the module for Modx look like a possibility to anyone? It would be a good bridge with the nonprofit tech community. In a way, these guys did the same thing with CiviCRM and Drupal that ModX did with--what was that other software’s name again?

For reference:
"CiviCRM is the first open source and freely downloadable constituent relationship management solution. CiviCRM is web-based, open source, internationalized, and designed specifically to meet the needs of advocacy, non-profit and non-governmental groups.
CiviCRM is a powerful contact, fundraising and eCRM system that allows you to record and manage information about your various constituents including volunteers, activists, donors, employees, clients, vendors, etc. Track and execute donations, transactions, conversations, events or any type of correspondence with each constituent and store it all in one, easily accessible and manageable source.
CiviCRM is created by an open source community coordinated by the 501-c-3 nonprofit Social Source Foundation. "
From:
http://www.openngo.org/aboutcivicrm