I hesitate to give advice on an IIS install, but corrupted files happen more often than you might think since MODx uses literally thousands of files.
I really think you should ask in the MODx IIS forum first, though (if you haven’t already), and see what people there have to say. For all I know, this might be a common problem there.
Bob, I appreciate your help. I will continue this over there.
http://modxcms.com/forums/index.php/topic,46319.0.html
Thanks, Thomas
"Remember what Bilbo used to say: It's a dangerous business, Frodo, going out your door. You step onto the road, and if you don't keep your feet, there's no knowing where you might be swept off to."
-J.R.R. Tolkien from The Lord of the Rings