I think it would be a better idea to use a template with a standard layout, something like this:
http://www.planetphotoshop.com/ or like this
http://mashable.com
The template should be nice but also as simple as possible, otherwise it is hard to modify.
1. On the left (home page) a featured article plus latest articles (each one with tags, author, publish date, number of comments on it, share buttons) and the pagination on the bottom.
2. On the right categories or archives, top comments, latest comments, most viewed articles, ajax twitter widget (kind of) and a free squared space for adverts.
3. The article page shoud have share buttons, tags, publish buttons, comments, related post, etc.
I’d like to design the template but I don’t know html5 yet, is that a requirement?